Recently, a video was released discussing how the theory of arterial acceleration is part of the ongoing scientific quest for a better understanding of cardiovascular physiology. This quest started with Galen in the 2nd century, is greatly furthered by Harvey in the 17th century as well as by various investigators at the end of the 19th century. The theory of acceleration adds to conceptual thinking about the role of the arterial system in cardiovascular physiology. It challenges a too simplistic view on arterial blood pressure.